Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Neurog2  neurogenin 2   (Synonyms: Atoh4, bHLHa8, Math4A, ngn2)
Results	Reference
1	J:284118 Ahmed M, Marziali LN, Arenas E, Feltri ML, Ffrench-Constant C, Laminin alpha2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development. Development. 2019 Aug 29;146(16):dev172668
1	J:287136 Aslanpour S, Han S, Schuurmans C, Kurrasch DM, Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. J Neurosci. 2020 Apr 29;40(18):3549-3563
1	J:257081 Bai G, Chivatakarn O, Bonanomi D, Lettieri K, Franco L, Xia C, Stein E, Ma L, Lewcock JW, Pfaff SL, Presenilin-dependent receptor processing is required for axon guidance. Cell. 2011 Jan 7;144(1):106-18
1	J:185651 Bluske KK, Vue TY, Kawakami Y, Taketo MM, Yoshikawa K, Johnson JE, Nakagawa Y, beta-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus. Development. 2012 Aug;139(15):2692-702
1	J:174488 Britz O, Mattar P, Nguyen L, Langevin LM, Zimmer C, Alam S, Guillemot F, Schuurmans C, A role for proneural genes in the maturation of cortical progenitor cells. Cereb Cortex. 2006 Jul;16 Suppl 1:i138-51
1	J:175804 Brzezinski JA 4th, Kim EJ, Johnson JE, Reh TA, Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina. Development. 2011 Aug;138(16):3519-31
1	J:283931 Chang MY, Oh B, Choi JE, Sulistio YA, Woo HJ, Jo A, Kim J, Kim EH, Kim SW, Hwang J, Park J, Song JJ, Kwon OC, Henry Kim H, Kim YH, Ko JY, Heo JY, Lee MJ, Lee M, Choi M, Chung SJ, Lee HS, Lee SH, LIN28A loss of function is associated with Parkinson's disease pathogenesis. EMBO J. 2019 Dec 16;38(24):e101196
1	J:244825 Dennis DJ, Wilkinson G, Li S, Dixit R, Adnani L, Balakrishnan A, Han S, Kovach C, Gruenig N, Kurrasch DM, Dyck RH, Schuurmans C, Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4934-E4943
1	J:205579 Dixit R, Wilkinson G, Cancino GI, Shaker T, Adnani L, Li S, Dennis D, Kurrasch D, Chan JA, Olson EC, Kaplan DR, Zimmer C, Schuurmans C, Neurog1 and Neurog2 control two waves of neuronal differentiation in the piriform cortex. J Neurosci. 2014 Jan 8;34(2):539-53
1*	J:188692 Dixit R, Zimmer C, Waclaw RR, Mattar P, Shaker T, Kovach C, Logan C, Campbell K, Guillemot F, Schuurmans C, Ascl1 participates in Cajal-Retzius cell development in the neocortex. Cereb Cortex. 2011 Nov;21(11):2599-611
1	J:124122 Ferri AL, Lin W, Mavromatakis YE, Wang JC, Sasaki H, Whitsett JA, Ang SL, Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner. Development. 2007 Aug;134(15):2761-9
1*	J:249803 Guerrero-Flores G, Bastidas-Ponce A, Collazo-Navarrete O, Guerra-Crespo M, Covarrubias L, Functional determination of the differentiation potential of ventral mesencephalic neural precursor cells during dopaminergic neurogenesis. Dev Biol. 2017 Sep 1;429(1):56-70
1*	J:293446 Han S, Dennis DJ, Balakrishnan A, Dixit R, Britz O, Zinyk D, Touahri Y, Olender T, Brand M, Guillemot F, Kurrasch D, Schuurmans C, A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis. Development. 2018 Oct 1;145(19):dev157719
1	J:310880 Han S, Okawa S, Wilkinson GA, Ghazale H, Adnani L, Dixit R, Tavares L, Faisal I, Brooks MJ, Cortay V, Zinyk D, Sivitilli A, Li S, Malik F, Ilnytskyy Y, Angarica VE, Gao J, Chinchalongporn V, Oproescu AM, Vasan L, Touahri Y, David LA, Raharjo E, Kim JW, Wu W, Rahmani W, Chan JA, Kovalchuk I, Attisano L, Kurrasch D, Dehay C, Swaroop A, Castro DS, Biernaskie J, Del Sol A, Schuurmans C, Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding. Neuron. 2021 Sep 15;109(18):2847-2863.e11
1	J:176240 Hand R, Polleux F, Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum. Neural Dev. 2011;6:30
1	J:231976 Hashimoto H, Ishino Y, Jiang W, Yoshimura T, Takeda-Uchimura Y, Uchimura K, Kadomatsu K, Ikenaka K, Keratan Sulfate Regulates the Switch from Motor Neuron to Oligodendrocyte Generation During Development of the Mouse Spinal Cord. Neurochem Res. 2016 Feb;41(1-2):450-62
1	J:139170 Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R, Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development. 2008 Aug;135(15):2531-41
1	J:258267 Jovanovic VM, Salti A, Tilleman H, Zega K, Jukic MM, Zou H, Friedel RH, Prakash N, Blaess S, Edenhofer F, Brodski C, BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells. J Neurosci. 2018 Feb 14;38(7):1662-1676
1	J:331939 Keil JM, Doyle DZ, Qalieh A, Lam MM, Funk OH, Qalieh Y, Shi L, Mohan N, Sorel A, Kwan KY, Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nat Commun. 2020 Jul 31;11(1):3839
1	J:203109 Konno D, Iwashita M, Satoh Y, Momiyama A, Abe T, Kiyonari H, Matsuzaki F, The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex. PLoS One. 2012;7(10):e46577
1	J:284155 Konno D, Kishida C, Maehara K, Ohkawa Y, Kiyonari H, Okada S, Matsuzaki F, Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes. Development. 2019 Aug 13;146(15):dev174243
1	J:241293 Marinaro F, Marzi MJ, Hoffmann N, Amin H, Pelizzoli R, Niola F, Nicassio F, De Pietri Tonelli D, MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression. EMBO Rep. 2017 Apr;18(4):603-618
1	J:157957 Nakatani T, Kumai M, Mizuhara E, Minaki Y, Ono Y, Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon. Dev Biol. 2010 Mar 1;339(1):101-13
1	J:124115 Nakatani T, Minaki Y, Kumai M, Ono Y, Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon. Development. 2007 Aug;134(15):2783-93
1	J:198671 Nelson BR, Hodge RD, Bedogni F, Hevner RF, Dynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: potential role in Dll1-Notch signaling. J Neurosci. 2013 May 22;33(21):9122-39
1	J:231849 Nouri N, Patel MJ, Joksimovic M, Poulin JF, Anderegg A, Taketo MM, Ma YC, Awatramani R, Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors. Mol Cell Neurosci. 2015 Sep;68:131-42
1	J:143341 Omodei D, Acampora D, Mancuso P, Prakash N, Di Giovannantonio LG, Wurst W, Simeone A, Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon. Development. 2008 Oct;135(20):3459-70
1	J:160534 Ono Y, Nakatani T, Minaki Y, Kumai M, The basic helix-loop-helix transcription factor Nato3 controls neurogenic activity in mesencephalic floor plate cells. Development. 2010 Jun;137(11):1897-906
1	J:124270 Ono Y, Nakatani T, Sakamoto Y, Mizuhara E, Minaki Y, Kumai M, Hamaguchi A, Nishimura M, Inoue Y, Hayashi H, Takahashi J, Imai T, Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells. Development. 2007 Sep;134(17):3213-25
1	J:241830 Sakane F, Miyamoto Y, N-cadherin regulates the proliferation and differentiation of ventral midbrain dopaminergic progenitors. Dev Neurobiol. 2013 Jul;73(7):518-29
1*	J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
1	J:193342 Schmidt-Strassburger U, Schips TG, Maier HJ, Kloiber K, Mannella F, Braunstein KE, Holzmann K, Ushmorov A, Liebau S, Boeckers TM, Wirth T, Expression of constitutively active FoxO3 in murine forebrain leads to a loss of neural progenitors. FASEB J. 2012 Dec;26(12):4990-5001
1*	J:210661 Seto Y, Ishiwata S, Hoshino M, Characterization of Olig2 expression during cerebellar development. Gene Expr Patterns. 2014 May;15(1):1-7
1	J:227685 Shimojo H, Isomura A, Ohtsuka T, Kori H, Miyachi H, Kageyama R, Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Genes Dev. 2016 Jan 1;30(1):102-16
1	J:135146 Shimojo H, Ohtsuka T, Kageyama R, Oscillations in notch signaling regulate maintenance of neural progenitors. Neuron. 2008 Apr 10;58(1):52-64
1	J:149534 Tang M, Miyamoto Y, Huang EJ, Multiple roles of {beta}-catenin in controlling the neurogenic niche for midbrain dopamine neurons. Development. 2009 Jun;136(12):2027-38
1	J:161771 Tang M, Villaescusa JC, Luo SX, Guitarte C, Lei S, Miyamoto Y, Taketo MM, Arenas E, Huang EJ, Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. J Neurosci. 2010 Jul 7;30(27):9280-91
1	J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5
1	J:162846 Teissier A, Griveau A, Vigier L, Piolot T, Borello U, Pierani A, A novel transient glutamatergic population migrating from the pallial-subpallial boundary contributes to neocortical development. J Neurosci. 2010 Aug 4;30(31):10563-74
1	J:107825 Thompson LH, Andersson E, Jensen JB, Barraud P, Guillemot F, Parmar M, Bjorklund A, Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon. Exp Neurol. 2006 Mar;198(1):183-98
1	J:132518 Vue TY, Aaker J, Taniguchi A, Kazemzadeh C, Skidmore JM, Martin DM, Martin JF, Treier M, Nakagawa Y, Characterization of progenitor domains in the developing mouse thalamus. J Comp Neurol. 2007 Nov 1;505(1):73-91
1	J:147427 Vue TY, Bluske K, Alishahi A, Yang LL, Koyano-Nakagawa N, Novitch B, Nakagawa Y, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97
1	J:147161 Wang B, Waclaw RR, Allen ZJ 2nd, Guillemot F, Campbell K, Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev. 2009;4:5
1	J:178621 Wang L, Bluske KK, Dickel LK, Nakagawa Y, Basal progenitor cells in the embryonic mouse thalamus - their molecular characterization and the role of neurogenins and Pax6. Neural Dev. 2011;6:35
1	J:176226 Yan CH, Levesque M, Claxton S, Johnson RL, Ang SL, Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. J Neurosci. 2011 Aug 31;31(35):12413-25
1	J:242450 Yang Q, Liu S, Yin M, Yin Y, Zhou G, Zhou J, Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse. Dev Neurobiol. 2015 Nov;75(11):1282-94
1	J:117465 Zhang J, Pho V, Bonasera SJ, Holtzman J, Tang AT, Hellmuth J, Tang S, Janak PH, Tecott LH, Huang EJ, Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons. Nat Neurosci. 2007 Jan;10(1):77-86